Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019798 | 1.00 | KMT2A (0.41) | KMT2APIN1RIPK1CYP3A4CYP2C19 | |
| SCHEMBL23721690 | 0.86 | KMT2A (0.42) | KMT2APIN1RIPK1CYP3A4CYP2C19 | |
| SCHEMBL903864 | 0.82 | KMT2A (0.40) | KMT2APIN1RIPK1CYP3A4CYP2C19 | |
| SCHEMBL28185307 | 0.80 | SMN1; SMN2 (0.44) | PIN1RIPK1DPP4CES2CES1 | |
| SCHEMBL16815808 | 0.80 | SMN1; SMN2 (0.44) | PIN1RIPK1DPP4CES2CES1 | |
| SCHEMBL29097178 | 0.76 | GPR84 (0.52) | RIPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL24327763 | 0.76 | GPR84 (0.52) | RIPK1ALDH1A1KDM4ELMNA | |
| SCHEMBL22112689 | 0.76 | NLRP3 (0.46) | KMT2AMEN1POLBLMNAMAPK1 | |
| SCHEMBL28019768 | 0.76 | KMT2A (0.46) | KMT2AMEN1GAAALDH1A1KDM4E | |
| SCHEMBL6224100 | 0.76 | NLRP3 (0.46) | KMT2AMEN1POLBLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |