Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702319 | 0.80 | HSD11B1 (0.43) | KIF11GLAPOLBGAATSHR | |
| SCHEMBL28676412 | 0.80 | TSHR (0.56) | GPR3EDNRBEDNRAKIF11GLA | |
| SCHEMBL28685875 | 0.79 | GAA (0.43) | GPR3EDNRBEDNRACYP17A1KIF11 | |
| SCHEMBL29538508 | 0.78 | SCN9A (0.43) | GPR3KIF11TSHRSCN9A | |
| SCHEMBL17950067 | 0.78 | KIF11 (0.44) | GPR3EDNRBEDNRAKIF11EPHX2 | |
| SCHEMBL11976481 | 0.77 | CNR2 (0.46) | CNR2KCNJ11SCN9AALOX5APFEN1 | |
| SCHEMBL17950242 | 0.77 | KIF11 (0.41) | GPR3EDNRBEDNRAKIF11EPHX2 | |
| SCHEMBL13298630 | 0.77 | PSD (0.44) | GPR3KIF11CNR2CYP1A1CYP1A2 | |
| SCHEMBL13298632 | 0.77 | PSD (0.44) | GPR3KIF11CNR2CYP1A1CYP1A2 | |
| SCHEMBL13849066 | 0.76 | ACP1 (0.38) | CYP17A1GAAHSD11B1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103254250-B | Ferrocenyl pyridine cyclic Pd-N heterocyclic carbene compound as well as preparation method and application thereof | UNIV LUOYANG NORMAL | 2015-06-10 | — | — | CN | disclosed |