Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL27973466 | 0.98 | TSHR (0.57) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Dimethylformamide SCHEMBL28265465 | 0.93 | BCL2L1 (0.54) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Terephthalic Acid SCHEMBL28297613 | 0.91 | TSHR (0.50) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Paraben SCHEMBL27658245 | 0.91 | CA2 (0.67) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Benzoic Acid SCHEMBL11321275 | 0.91 | TSHR (0.64) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Dimethylformamide SCHEMBL28173355 | 0.89 | TSHR (0.48) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Dimethylformamide SCHEMBL27678362 | 0.89 | RAB9A (0.55) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 | |
| Dimethylformamide SCHEMBL27547505 | 0.88 | EGFR (0.55) | TSHRALDH1A1SMN1; SMN2SRD5A2NPC1 | |
| Dimethylformamide SCHEMBL28836537 | 0.85 | TPMT (0.48) | TSHRTP53ALDH1A1SMN1; SMN2CA1 | |
| Terephthalic Acid SCHEMBL9407875 | 0.84 | TSHR (0.75) | TSHRTP53ALDH1A1SMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133924-B | Material for measuring microscopic hot spots in microwave field, application and method | 天津大学 | 2023-12-29 | — | — | CN | claimed |
| CN-108586501-A | A kind of Zn complex and the preparation method and application thereof | 北京石油化工学院 | 2018-09-28 | — | — | CN | disclosed |
| CN-103709031-B | Method for recycling terephthalic acid using colored polyester | UNIV HEFEI TECHNOLOGY | 2015-05-27 | — | — | CN | disclosed |