Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | YWHAG | P61981 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CDC7 | O00311 | 2/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3083169 | 0.74 | NPC1 (1.00) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL605593 | 0.74 | NPC1 (1.00) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL31565663 | 0.72 | NPC1 (0.96) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL3654065 | 0.72 | NPC1 (0.96) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL3538450 | 0.70 | NPC1 (0.63) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL28325509 | 0.70 | HTT (0.71) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL5318789 | 0.70 | NPC1 (0.46) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL17774829 | 0.70 | HTT (1.00) | NPC1HTTKDM4EMAPTHSD17B10 | |
| SCHEMBL2505914 | 0.70 | NPC1 (0.73) | NPC1HTTKDM4EMAPTHSD17B10 | |
| Pyrrole SCHEMBL28237296 | 0.70 | NPC1 (0.60) | NPC1HTTKDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829592-B | The synthetic method of 4 piperidyl 1H pyrroles, 3 Carbox amide hydrochloride | 河南科技大学第附属医院 | 2017-03-15 | — | — | CN | claimed |
| CN-104829592-A | Synthesis method of 4-piperidyl-1H-pyrrole-3-formamide compound hydrochloride | 1ST AFFILIATED HOSPITAL HENAN UNIV SCIENCE & TECHNOLOGY | 2015-08-12 | — | — | CN | claimed |
| CN-104829592-B | The synthetic method of 4 piperidyl 1H pyrroles, 3 Carbox amide hydrochloride | 河南科技大学第附属医院 | 2017-03-15 | — | — | CN | disclosed |
| CN-104829592-A | Synthesis method of 4-piperidyl-1H-pyrrole-3-formamide compound hydrochloride | 1ST AFFILIATED HOSPITAL HENAN UNIV SCIENCE & TECHNOLOGY | 2015-08-12 | — | — | CN | disclosed |