Pyrrole

Pyrrole

SCHEMBL28237296

Cc1c(C(N)=O)cccc1N1CCCCC1.c1cc[nH]c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.60
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 4/20 0.43
KDM4E B2RXH2 1/20 0.43
THRB P10828 1/20 0.43
ALOX15 P16050 1/20 0.43
GFER P55789 1/20 0.43
YWHAG P61981 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 2/20 0.43
ALDH1A1 P00352 3/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
PARP1 P09874 6/20 0.40
NPSR1 Q6W5P4 2/20 0.40
TSHR P16473 1/20 0.40
BTK Q06187 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20587384 0.92 NPC1 (0.71) NPC1MEN1KMT2ALMNAHTT
SCHEMBL28793930 0.87 NPC1 (0.63) NPC1MEN1KMT2ALMNAHTT
SCHEMBL3436295 0.81 NPC1 (0.51) NPC1MEN1KMT2ALMNAMAPT
SCHEMBL1742844 0.80 ADRB1 (0.59) NPC1HSD17B10TSHR
SCHEMBL6105727 0.78 NPC1 (0.54) NPC1MEN1KMT2ALMNAHTT
SCHEMBL2612163 0.78 NPC1 (0.54) NPC1MEN1KMT2ALMNAHTT
SCHEMBL10854322 0.77 NPC1 (0.50) NPC1MEN1KMT2ALMNAHTT
SCHEMBL5532619 0.76 NPC1 (0.51) NPC1MEN1KMT2ALMNAMAPT
SCHEMBL605593 0.76 NPC1 (1.00) NPC1MEN1KMT2AHTTMAPT
SCHEMBL3083169 0.76 NPC1 (1.00) NPC1MEN1KMT2AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108472617-A Include the microcapsules of polyester-urethane shell and hydrophilic nuclear material 巴斯夫欧洲公司 2018-08-31 CN disclosed
CN-108472616-A Include the microcapsules of polyester-urethane shell and hydrophobic nuclear material 巴斯夫欧洲公司 2018-08-31 CN disclosed