SCHEMBL28020140

SCHEMBL28020140

CCC1CO1.CCCOC(=O)c1ccccc1C

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
TSHR P16473 6/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
TDP1 Q9NUW8 3/20 0.49
CYP3A4 P08684 2/20 0.48
MAPK1 P28482 2/20 0.48
TP53 P04637 1/20 0.48
LMNA P02545 2/20 0.47
KDM4E B2RXH2 3/20 0.44
MAOB P27338 1/20 0.44
HSD17B10 Q99714 4/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
BCHE P06276 1/20 0.42
POLB P06746 1/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28020535 0.92 TSHR (0.61) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
SCHEMBL1629684 0.87 ALDH1A1 (0.79) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
SCHEMBL28020526 0.84 ALDH1A1 (0.59) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
Alcohol SCHEMBL27463083 0.84 ALDH1A1 (0.73) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
SCHEMBL28020077 0.82 ALDH1A1 (0.61) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
SCHEMBL9770446 0.81 DHFR (0.54) ALDH1A1TSHRL3MBTL1TDP1MAPK1
SCHEMBL28020075 0.81 KDM4E (0.49) ALDH1A1TSHRL3MBTL1TDP1KDM4E
SCHEMBL17797782 0.78 TSHR (0.66) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
SCHEMBL29822410 0.78 ALDH1A1 (0.64) ALDH1A1TSHRL3MBTL1TDP1CYP3A4
SCHEMBL18499669 0.78 ALDH1A1 (0.64) ALDH1A1TSHRL3MBTL1TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829756-B A kind of solid catalyst component for olefine polymerization and its preparation method and application 中国科学院化学研究所 2018-05-15 CN disclosed
CN-104829756-A Solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed