Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28020164

ClOCl.NNc1ccccc1C(=O)O.S

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 4/20 0.50
ALDH1A1 P00352 4/20 0.48
ALOX15 P16050 1/20 0.48
HPGD P15428 3/20 0.48
MAPT P10636 3/20 0.48
KDM4E B2RXH2 3/20 0.48
POLB P06746 2/20 0.48
GAA P10253 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PBRM1 Q86U86 1/20 0.47
FABP3 P05413 2/20 0.47
FABP5 Q01469 2/20 0.47
HSD17B10 Q99714 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
TTR P02766 2/20 0.46
CDC25B P30305 1/20 0.46
USP2 O75604 1/20 0.46
MT-CO2 P00403 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL143766 0.90 ALDH1A1 (0.59) FABP4ALDH1A1ALOX15HPGDMAPT
Hydrochloric Acid SCHEMBL1522753 0.88 FABP4 (0.57) FABP4ALDH1A1ALOX15HPGDMAPT
Hydrochloric Acid SCHEMBL27997789 0.88 FABP4 (0.57) FABP4ALDH1A1ALOX15HPGDMAPT
Bromide SCHEMBL20984528 0.88 FABP4 (0.57) FABP4ALDH1A1ALOX15HPGDMAPT
Oxalic Acid SCHEMBL20984889 0.86 FABP4 (0.55) FABP4ALDH1A1ALOX15HPGDMAPT
Sulfuric Acid SCHEMBL20984856 0.82 FABP4 (0.52) FABP4ALDH1A1ALOX15HPGDMAPT
Phosphoric Acid SCHEMBL20984773 0.82 FABP4 (0.52) FABP4ALDH1A1ALOX15HPGDMAPT
Acetic Acid SCHEMBL27992671 0.82 FABP4 (0.52) FABP4ALDH1A1ALOX15HPGDMAPT
Methylglyoxal SCHEMBL8854648 0.79 DHODH (0.51) FABP4ALDH1A1ALOX15HPGDMAPT
Nitric Acid SCHEMBL20984574 0.79 ALDH1A1 (0.57) FABP4ALDH1A1ALOX15HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829683-A Indole skeleton-containing dihydropyrazolpiperazine C21 steroid sapogenin derivative, and preparation method and application thereof JIANGSU NATURE BIOLOG ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN claimed
CN-104829682-A Furan-skeleton-containing 2H-pyrazole piperazine C21 steroidal saponin aglycone derivatives, preparation method, and applications thereof JIANGSU NATURE BIOLOG ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN claimed
CN-104788531-A Dihydro pyrazol piperazine C21 steroid saponin aglycone derivative containing thiophene backbone as well as preparation method and application thereof JIANGSU NATURE BIOLOG ENGINEERING TECHNOLOGY CO LTD 2015-07-22 CN claimed
CN-104829683-A Indole skeleton-containing dihydropyrazolpiperazine C21 steroid sapogenin derivative, and preparation method and application thereof JIANGSU NATURE BIOLOG ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN disclosed
CN-104829682-A Furan-skeleton-containing 2H-pyrazole piperazine C21 steroidal saponin aglycone derivatives, preparation method, and applications thereof JIANGSU NATURE BIOLOG ENGINEERING TECHNOLOGY CO LTD 2015-08-12 CN disclosed
CN-104788531-A Dihydro pyrazol piperazine C21 steroid saponin aglycone derivative containing thiophene backbone as well as preparation method and application thereof JIANGSU NATURE BIOLOG ENGINEERING TECHNOLOGY CO LTD 2015-07-22 CN disclosed