Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28195348 | 1.00 | MEN1 (0.53) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL965059 | 0.97 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL4859 | 0.97 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL29422639 | 0.97 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL28517984 | 0.95 | MEN1 (0.53) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL28173309 | 0.95 | MEN1 (0.53) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL4019358 | 0.92 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL15263131 | 0.92 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2MMP9 | |
| Oxalic Acid SCHEMBL29186473 | 0.86 | THRB (0.43) | MEN1KMT2ATHRBMMP2MMP9 | |
| Pyruvate SCHEMBL3172393 | 0.85 | CA4 (0.48) | MEN1KMT2ATHRBMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829653-B | A kind of oxaliplatin hydrate crystal and lyophilized injectable powder thereof | Shandong Luo Xin Pharmaceutical Group Plc (CN) | 2016-03-23 | — | — | CN | claimed |
| CN-104829653-A | Oxaliplatin hydrate crystal and freeze-dried powder injection | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-105705152-B | Lipid-based platinum compounds and nanoparticles | 阿卡玛拉疗法有限公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-104829653-B | A kind of oxaliplatin hydrate crystal and lyophilized injectable powder thereof | Shandong Luo Xin Pharmaceutical Group Plc (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-104829653-B | A kind of oxaliplatin hydrate crystal and lyophilized injectable powder thereof | Shandong Luo Xin Pharmaceutical Group Plc (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-104829653-B | A kind of oxaliplatin hydrate crystal and lyophilized injectable powder thereof | Shandong Luo Xin Pharmaceutical Group Plc (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-105250317-A | Antitumor drug oxaliplatin composition | QINGDAO HUAZHICAO PHARMACEUTICAL CO LTD | 2016-01-20 | — | — | CN | disclosed |
| CN-105125532-A | Medicament oxaliplatin composition for treating cancers | QINGDAO HUAZHICAO PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-12-09 | — | — | CN | disclosed |
| CN-105078953-A | Anticancer oxaliplatin composition | YANG XIANMEI | 2015-11-25 | — | — | CN | disclosed |
| CN-105055347-A | Oxaliplatin composition freeze-dried powder injection for treating metastatic colorectal cancers | QINGDAO HUAZHICAO PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-105055324-A | Platinum anticancer oxaliplatin composition | QINGDAO HUAZHICAO PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-105055308-A | Platinum-based antitumor drug oxaliplatin composition liquid injection | QINGDAO HUAZHICAO PHARMACEUTICAL CO LTD | 2015-11-18 | — | — | CN | disclosed |
| CN-104940151-A | Oxaliplatin freeze-dried powder injection composition as anti-cancer drug | QINGDAO LANSHENGYANG MEDICINE BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-09-30 | — | — | CN | disclosed |
| CN-104945443-A | Drug, namely oxaliplatin compound, for treating cancer | QINGDAO LANSHENGYANG MEDICINE BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2015-09-30 | — | — | CN | disclosed |
| CN-104829653-A | Oxaliplatin hydrate crystal and freeze-dried powder injection | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-08-12 | — | — | CN | disclosed |
| CN-104829653-A | Oxaliplatin hydrate crystal and freeze-dried powder injection | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-08-12 | — | — | CN | disclosed |
| CN-104829653-A | Oxaliplatin hydrate crystal and freeze-dried powder injection | SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD | 2015-08-12 | — | — | CN | disclosed |