Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL965059 | 1.00 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2CA12 | |
| Oxalic Acid SCHEMBL4859 | 1.00 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2CA12 | |
| Oxalic Acid SCHEMBL28517984 | 0.97 | MEN1 (0.53) | MEN1KMT2ATHRBMMP2CA12 | |
| Oxalic Acid SCHEMBL15263131 | 0.94 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2CA12 | |
| Oxalic Acid SCHEMBL4019358 | 0.94 | MEN1 (0.56) | MEN1KMT2ATHRBMMP2CA12 | |
| Oxalic Acid SCHEMBL29186473 | 0.89 | THRB (0.43) | MEN1KMT2ATHRBMMP2CA12 | |
| Pyruvate SCHEMBL3172393 | 0.87 | CA4 (0.48) | MEN1KMT2ATHRBMMP2CA12 | |
| Malonic Acid SCHEMBL2174031 | 0.82 | CA4 (0.48) | MEN1KMT2ATHRBMMP2CA12 | |
| Acetic Acid SCHEMBL29253911 | 0.81 | MEN1 (0.53) | MEN1KMT2ATHRBMMP2CA12 | |
| Acetic Acid SCHEMBL10590524 | 0.81 | MEN1 (0.53) | MEN1KMT2ATHRBMMP2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117717565-A | Application of antisense oligonucleotide in preparing medicament for treating esophagus cancer | 北京悦康科创医药科技股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| EP-3973064-A2 | GENETIC AMPLIFIED TUMOR HOMING NANOPARTICLES AND COMPOSITIONS AND METHODS THEREOF | University of Massachusetts (US) | 2022-03-30 | — | — | EP | claimed |
| US-12638451-B2 | Genetic amplified tumor homing nanoparticles and compositions and methods thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2026-05-26 | — | — | US | disclosed |
| CN-117717565-A | Application of antisense oligonucleotide in preparing medicament for treating esophagus cancer | 北京悦康科创医药科技股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| US-11433136-B2 | Polyacetal polymers, conjugates, particles and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2022-09-06 | — | — | US | disclosed |
| CN-113908292-B | Target-mediated nucleic acid nano preparation and preparation method thereof | 南京吉迈生物技术有限公司 | 2022-08-16 | — | — | CN | disclosed |
| US-20220178928-A1 | GENETIC AMPLIFIED TUMOR HOMING NANOPARTICLES AND COMPOSITIONS AND METHODS THEREOF | UNIV MASSACHUSETTS (US) | 2022-06-09 | — | — | US | disclosed |
| EP-3973064-A2 | GENETIC AMPLIFIED TUMOR HOMING NANOPARTICLES AND COMPOSITIONS AND METHODS THEREOF | University of Massachusetts (US) | 2022-03-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12638451-B2 | Genetic amplified tumor homing nanoparticles and compositions and methods thereof | KLK3, TFRC, HAVCR2 | MEN1 3404/4885KMT2A 4288/4885THRB 1666/4885 |
| US-11433136-B2 | Polyacetal polymers, conjugates, particles and uses thereof | CD44, FUT6, MSN | MEN1 1997/4885KMT2A 2523/4885THRB 4284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.