Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 3/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MATK | P42679 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516259 | 0.85 | CYP1A2 (0.45) | CYP1A2CYP2C19CCR4PDPK1MTNR1A | |
| SCHEMBL14516263 | 0.82 | HRH4 (0.52) | CCR4PDPK1 | |
| SCHEMBL91582 | 0.81 | MKNK1 (0.51) | MKNK1MKNK2KCNH3ALDH1A1CYP1A2 | |
| SCHEMBL28860465 | 0.81 | MKNK1 (0.42) | MKNK1CYP1A2CYP2C19CCR4PDPK1 | |
| SCHEMBL19477216 | 0.80 | MKNK1 (0.50) | MKNK1MKNK2KCNH3ALDH1A1CYP1A2 | |
| SCHEMBL11308784 | 0.80 | MKNK1 (0.53) | MKNK1MKNK2KCNH3ALDH1A1CYP1A2 | |
| SCHEMBL10055017 | 0.79 | CLK4 (0.52) | MAPK9CLK2CLK4 | |
| SCHEMBL10026853 | 0.78 | MKNK1 (0.46) | MKNK1MKNK2KCNH3ALDH1A1CYP1A2 | |
| SCHEMBL12280402 | 0.78 | DYRK1B (0.46) | CCR4PDPK1 | |
| SCHEMBL24650717 | 0.78 | MKNK1 (0.48) | MKNK1MKNK2KCNH3ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104725397-A | Thienopyrimidine derivatives, a process for their preparation and pharmaceutical compositions containing them | SERVIER LAB | 2015-06-24 | — | — | CN | disclosed |