Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14516259 | 0.86 | CYP1A2 (0.45) | CYP1A2CYP2C19MTNR1AMTNR1BPDPK1 | |
| SCHEMBL10055017 | 0.84 | CLK4 (0.52) | HTTCLK1CLK2DYRK1ACLK4 | |
| SCHEMBL26550296 | 0.83 | ALDH1A1 (0.40) | MKNK1L3MBTL1BLMHTTCYP1A2 | |
| SCHEMBL14516263 | 0.83 | HRH4 (0.52) | PDPK1CCR4 | |
| SCHEMBL28020340 | 0.81 | MKNK1 (0.50) | MKNK1CYP1A2CYP2C19MTNR1AMTNR1B | |
| SCHEMBL10055031 | 0.80 | SMN1; SMN2 (0.49) | HTTSYKCLK1CLK2DYRK1A | |
| SCHEMBL5622348 | 0.80 | HTT (0.61) | MKNK1L3MBTL1HTTCYP1A2CYP2C19 | |
| SCHEMBL3265737 | 0.79 | HTR3A (0.39) | CYP1A2MTNR1AMTNR1BSYKMAPT | |
| SCHEMBL24440931 | 0.78 | SYK (0.43) | HTTCYP1A2PDPK1CCR4SYK | |
| SCHEMBL24440661 | 0.78 | CCR4 (0.39) | MKNK1L3MBTL1BLMHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104428293-B | Adjust the benzimidazole of TNF α | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |