Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020483 | 0.81 | SCN9A (0.45) | SCN9ARAB9A | |
| SCHEMBL27485822 | 0.79 | SCN9A (0.47) | SCN9ALMNATSHRRAB9A | |
| SCHEMBL289669 | 0.77 | KLK5 (0.53) | SCN9AKMT2AL3MBTL1 | |
| SCHEMBL16462573 | 0.77 | KLK5 (0.53) | SCN9AKMT2AL3MBTL1 | |
| SCHEMBL3836761 | 0.77 | KLK5 (0.53) | SCN9AKMT2AL3MBTL1 | |
| SCHEMBL28837742 | 0.76 | SCN9A (0.47) | SCN9ARAB9A | |
| SCHEMBL28837747 | 0.76 | SCN9A (0.47) | SCN9ARAB9A | |
| SCHEMBL28820188 | 0.75 | CTSL (0.44) | SCN9ARAB9A | |
| SCHEMBL5404351 | 0.75 | BCHE (0.43) | SCN9ACTSDRAB9A | |
| SCHEMBL5404358 | 0.75 | BCHE (0.43) | SCN9ACTSDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837858-A | Ketoamide immunoproteasome inhibitors | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |