Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.44 |
| ▸ | CTSK | P43235 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | CTSC | P53634 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CTSH | P09668 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27485822 | 0.84 | SCN9A (0.47) | CTSLCTSKCTSBSCN9ACTSS | |
| SCHEMBL28020483 | 0.81 | SCN9A (0.45) | CTSLCTSKCTSBSCN9ACTSS | |
| SCHEMBL28837742 | 0.81 | SCN9A (0.47) | CTSLCTSKCTSBSCN9ACTSS | |
| SCHEMBL28837747 | 0.81 | SCN9A (0.47) | CTSLCTSKCTSBSCN9ACTSS | |
| SCHEMBL28496647 | 0.78 | CTSC (0.44) | CTSLCTSKCTSBANPEPCTSC | |
| SCHEMBL28529219 | 0.78 | CTSC (0.44) | CTSLCTSKCTSBANPEPCTSC | |
| SCHEMBL5393871 | 0.77 | OPRM1 (0.45) | SCN9ANPC1RAB9AMAPT | |
| SCHEMBL5393866 | 0.77 | OPRM1 (0.45) | SCN9ANPC1RAB9AMAPT | |
| SCHEMBL28755814 | 0.76 | CYP3A4 (0.42) | SCN9A | |
| SCHEMBL28020511 | 0.75 | SCN9A (0.43) | SCN9ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104837858-A | Ketoamide immunoproteasome inhibitors | HOFFMANN LA ROCHE | 2015-08-12 | — | — | CN | disclosed |