SCHEMBL28020534

SCHEMBL28020534

CC(C)Oc1ccccc1C(=O)OOC(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IRAK4 Q9NWZ3 2/20 0.57
ALDH1A1 P00352 3/20 0.51
TDP1 Q9NUW8 2/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
KCNK3 O14649 2/20 0.44
KCNK9 Q9NPC2 2/20 0.44
ACHE P22303 1/20 0.43
IDO1 P14902 1/20 0.43
TDO2 P48775 1/20 0.43
RXFP1 Q9HBX9 2/20 0.40
HPGD P15428 1/20 0.38
XBP1 P17861 1/20 0.38
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ELANE P08246 1/20 0.38
HCRTR1 O43613 1/20 0.38
HCRTR2 O43614 1/20 0.38
KDM4E B2RXH2 2/20 0.38
PRMT5 O14744 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL263306 0.82 HSD17B10 (0.56) ALDH1A1TDP1TSHRHSD17B10HPGD
SCHEMBL29631091 0.81 TSHR (0.68) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL155434 0.81 TSHR (0.68) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL28020501 0.81 ALDH1A1 (0.47) ALDH1A1TDP1TSHRHSD17B10MAPT
SCHEMBL27958806 0.80 IRAK4 (0.68) IRAK4ALDH1A1TDP1TSHRHSD17B10
SCHEMBL11655234 0.79 TSHR (0.66) ALDH1A1TDP1TSHRHSD17B10ELANE
Benzene SCHEMBL12472151 0.79 TSHR (0.71) ALDH1A1TDP1TSHRHSD17B10ELANE
SCHEMBL29288745 0.79 HSD17B10 (0.53) IRAK4ALDH1A1TDP1TSHRHSD17B10
SCHEMBL10889050 0.79 ALDH1A1 (0.49) IRAK4ALDH1A1TDP1TSHRHSD17B10
SCHEMBL4036585 0.78 IRAK4 (0.66) IRAK4ALDH1A1TDP1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104829756-A Solid catalyst component for olefin polymerization, and preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2015-08-12 CN disclosed