Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27703396 | 0.86 | PLAU (0.46) | TSHRNPC1ALDH1A1CYP3A4LMNA | |
| SCHEMBL28020507 | 0.84 | TSHR (0.66) | TSHRL3MBTL1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL14974491 | 0.84 | TSHR (0.57) | TSHRL3MBTL1TDP1NPC1CCNB2 | |
| SCHEMBL28020068 | 0.84 | ALDH1A1 (0.55) | TSHRL3MBTL1TDP1CCNB2CCNE2 | |
| SCHEMBL28020064 | 0.83 | TSHR (0.59) | TSHRL3MBTL1TDP1CCNB2CCNE2 | |
| SCHEMBL28020514 | 0.83 | SCN4A (0.45) | TSHRNPC1ALDH1A1CYP3A4LMNA | |
| SCHEMBL382128 | 0.81 | KDM4E (0.57) | TSHRL3MBTL1TDP1NPC1CCNB2 | |
| SCHEMBL29196230 | 0.81 | NPC1 (0.50) | L3MBTL1NPC1ALDH1A1MAPK1LMNA | |
| SCHEMBL28020495 | 0.80 | TSHR (0.56) | TSHRL3MBTL1TDP1ALDH1A1CYP3A4 | |
| SCHEMBL14992204 | 0.80 | TSHR (0.58) | TSHRL3MBTL1TDP1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829756-B | A kind of solid catalyst component for olefine polymerization and its preparation method and application | 中国科学院化学研究所 | 2018-05-15 | — | — | CN | disclosed |
| CN-104829756-A | Solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |