Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27676707 | 0.94 | PTPN11 (0.56) | KDM4EALDH1A1HPGDHSD17B10PTPN11 | |
| SCHEMBL383490 | 0.92 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10PTPN11 | |
| SCHEMBL17980842 | 0.90 | TSHR (0.53) | KDM4EALDH1A1PTPN11TSHRTP53 | |
| SCHEMBL28602270 | 0.87 | ALDH1A1 (0.57) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL7695345 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL6948839 | 0.86 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13951454 | 0.85 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL1989131 | 0.85 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL14974491 | 0.84 | TSHR (0.57) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL28020507 | 0.84 | TSHR (0.66) | KDM4EALDH1A1HSD17B10TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829756-B | A kind of solid catalyst component for olefine polymerization and its preparation method and application | 中国科学院化学研究所 | 2018-05-15 | — | — | CN | disclosed |
| CN-104829756-A | Solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |
| US-8101625-B2 | Pyrimidinones as Casein Kinase II (CK2) modulators | EXELIXIS, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| EP-1948617-B1 | PYRIMIDINONES AS CASEIN KINASE II (CK2) MODULATORS | EXELIXIS INC (US) | 2011-07-27 | — | — | EP | disclosed |