Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316712 | 0.91 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| Ethylenediamine SCHEMBL27862580 | 0.82 | HTR1B (0.61) | ALDH1A1KDM4EHPGDTDP1KMT2A | |
| SCHEMBL28600804 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| SCHEMBL29037273 | 0.80 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| SCHEMBL275479 | 0.79 | SLC22A6 (0.51) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| SCHEMBL1692540 | 0.79 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| Ammonia Solution, Strong SCHEMBL10605012 | 0.78 | FABP1 (0.50) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| Water SCHEMBL2147729 | 0.78 | FABP1 (0.50) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| SCHEMBL3203462 | 0.77 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDTDP1HSD17B10 | |
| SCHEMBL2827392 | 0.77 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104761515-A | Crystalline forms of neurotrophin mimetic compounds and salts of same | PHARMATROPHIX INC | 2015-07-08 | — | — | CN | disclosed |