Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 1/20 | 0.35 |
| ▸ | GLRB | P48167 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31021567 | 0.81 | GLRA3 (0.39) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL1899129 | 0.74 | MEN1 (0.37) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL31021584 | 0.74 | DPP4 (0.36) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL25605788 | 0.74 | CYP1A2 (0.32) | — | |
| SCHEMBL31021576 | 0.72 | ESR1 (0.38) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL8517367 | 0.72 | ESR1 (0.38) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL19728375 | 0.71 | TAS1R3 (0.33) | — | |
| SCHEMBL23164220 | 0.71 | GLRA3 (0.48) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL28343560 | 0.71 | GLRA3 (0.48) | GLRA3GLRBDPP4CA12CA1 | |
| SCHEMBL721202 | 0.70 | ESR1 (0.41) | GLRA3GLRBDPP4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104853757-A | 4-heteroaryl substituted benzoic acid compounds as ROR gamma T inhibitors and uses thereof | MERCK SHARP & DOHME | 2015-08-19 | — | — | CN | disclosed |