Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 10/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 9/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 9/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19728858 | 0.84 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL2011531 | 0.80 | MEN1 (0.46) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL6578763 | 0.80 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL18774734 | 0.80 | CYP1A2 (0.41) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL7074989 | 0.78 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL503607 | 0.75 | TAS1R3 (0.47) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL19130691 | 0.75 | MEN1 (0.41) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL8374326 | 0.74 | LDHA (0.39) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL1753848 | 0.74 | — | — | |
| SCHEMBL2470702 | 0.73 | TAS1R3 (0.45) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017217441-A1 | NOVEL PYRIDONECARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | 湧永製薬株式会社 | 2017-12-21 | — | — | WO | disclosed |