SCHEMBL28020741

SCHEMBL28020741

O=P(c1ccccc1)(c1ccccc1)N(Cl)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 9/20 0.52
HTT P42858 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41
CA5A P35218 1/20 0.41
KCNN4 O15554 4/20 0.39
CFTR P13569 1/20 0.37
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.35
ALPG P10696 1/20 0.35
ALOX12 P18054 1/20 0.35
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
ALOX15 P16050 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28496199 0.74 HTT (0.44) KCNA5HTTMEN1KMT2ACA2
SCHEMBL14493541 0.73 MEN1 (0.74) KCNA5HTTMEN1KMT2ACA2
SCHEMBL14311022 0.71 KCNA5 (0.49) KCNA5HTTMEN1KMT2ACA2
SCHEMBL14938870 0.71 HTT (0.46) KCNA5HTTMEN1KMT2ACA2
Hydrochloric Acid SCHEMBL28465544 0.70 CA2 (0.48) KCNA5HTTMEN1KMT2ACA2
SCHEMBL3804423 0.69 CA2 (0.52) KCNA5HTTMEN1KMT2ACA2
SCHEMBL525867 0.69 MAPT (0.48) KCNA5HTTMEN1KMT2ACA2
SCHEMBL22756262 0.69 CA2 (0.46) KCNA5HTTMEN1KMT2ACA2
SCHEMBL12150822 0.67 HTT (0.46) KCNA5HTTMEN1KMT2ACA2
SCHEMBL10568061 0.67 MEN1 (0.58) HTTMEN1KMT2AALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103189061-B Be used for the treatment of 4-(methylamino phenoxy group) pyridin-3-yl-heterocyclic carbamate derivatives of cancer OTSUKA PHARMACEUTICAL CO.,LTD. (JP) 2015-09-02 CN disclosed