Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CBFB | Q13951 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL96680 | 0.75 | HTT (0.48) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| SCHEMBL28020741 | 0.74 | KCNA5 (0.52) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27416015 | 0.73 | HTT (0.46) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| SCHEMBL10935344 | 0.71 | HTT (0.70) | HTTKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL6686855 | 0.70 | HTT (0.43) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| SCHEMBL7078980 | 0.70 | HTT (0.43) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| SCHEMBL9386229 | 0.67 | LMNA (0.39) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| SCHEMBL11582842 | 0.67 | HTT (0.44) | HTTKMT2AMEN1KCNA5ALDH1A1 | |
| SCHEMBL991345 | 0.66 | — | — | |
| SCHEMBL15052257 | 0.65 | HTT (0.43) | HTTKMT2AMEN1KCNA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916822-A | Methods of using anti-CD 79b immunoconjugates | 基因泰克公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115427069-A | Reducing statistical bias in genetic sampling | 基金会医学公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115315256-A | Methods of treating cancer with anti-TIGIT antagonist antibodies | 基因泰克公司 | 2022-11-08 | — | — | CN | disclosed |
| CN-115210227-A | Heterobifunctional molecules as TEAD inhibitors | 基因泰克公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115087749-A | Method and system for molecular disease assessment by analysis of circulating tumor DNA | 莱森特生物公司 | 2022-09-20 | — | — | CN | disclosed |
| CN-115066613-A | Diagnostic and therapeutic methods for treating hematologic cancers | 基因泰克公司 | 2022-09-16 | — | — | CN | disclosed |
| CN-114945386-A | Methods of treating diffuse large B-cell lymphoma using anti-CD 79B immunoconjugates | 基因泰克公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-114728936-A | Bifunctional compounds for the treatment of cancer | 豪夫迈·罗氏有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114599428-A | Bifunctional compounds | 豪夫迈·罗氏有限公司 | 2022-06-07 | — | — | CN | disclosed |
| CN-114269376-A | Methods of treating cancer with anti-PD-L1 antibodies | 豪夫迈·罗氏有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113196061-A | Methods of diagnosis and treatment of sarcoma-like renal cancer | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-112805267-A | Carboxamide and sulfonamide derivatives as TEAD modulators | 豪夫迈·罗氏有限公司 | 2021-05-14 | — | — | CN | disclosed |
| CN-112585166-A | Methods of treating lung cancer with PD-1 axis binding antagonists, platinating agents, and topoisomerase II inhibitors | 豪夫迈·罗氏有限公司 | 2021-03-30 | — | — | CN | disclosed |
| CN-111587120-A | Immunogenic compositions and uses thereof | 艾比克斯治疗私人有限公司 | 2020-08-25 | — | — | CN | disclosed |