Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954219 | 0.79 | HSD11B1 (0.41) | CTSSSOS2CTSKIRAK4KCNH2 | |
| SCHEMBL29561378 | 0.79 | SOS2 (0.39) | CTSSSOS2CTSKIRAK4ALOX5AP | |
| SCHEMBL29413281 | 0.79 | CCR1 (0.40) | CTSSSOS2CTSKIRAK4ALOX5AP | |
| SCHEMBL14732983 | 0.79 | KCNH2 (0.44) | CTSSSOS2CTSKIRAK4KCNH2 | |
| SCHEMBL1758823 | 0.79 | SOS2 (0.43) | CTSSSOS2CTSK | |
| SCHEMBL9297038 | 0.79 | SOS2 (0.39) | CTSSSOS2CTSKIRAK4ALOX5AP | |
| SCHEMBL378968 | 0.79 | CCR1 (0.40) | CTSSSOS2CTSKIRAK4ALOX5AP | |
| SCHEMBL129485 | 0.79 | SOS2 (0.39) | CTSSSOS2CTSKIRAK4ALOX5AP | |
| SCHEMBL3760158 | 0.79 | IRAK4 (0.49) | CTSSSOS2CTSKIRAK4ALOX5AP | |
| SCHEMBL3354041 | 0.79 | KCNH2 (0.33) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736134-A | Compounds and methods for enhancing degradation of target proteins and other polypeptides by E3 ubiquitin ligases | 耶鲁大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-104736569-A | Compounds and methods for enhancing degradation of target proteins and other polypeptides by E3 ubiquitin ligase | UNIV YALE | 2015-06-24 | — | — | CN | disclosed |