Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PGK2 | P07205 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22031516 | 0.79 | PGK1 (0.32) | PGK1PGK2 | |
| SCHEMBL31732088 | 0.79 | CCR1 (0.40) | PGK1PGK2 | |
| SCHEMBL5236735 | 0.79 | KCNH2 (0.35) | KCNH2PGK1PGK2PDE2A | |
| SCHEMBL947116 | 0.79 | CCR1 (0.40) | PGK1PGK2 | |
| SCHEMBL3347186 | 0.77 | GRM5 (0.37) | — | |
| SCHEMBL982334 | 0.77 | CYP1A1 (0.37) | PDE2A | |
| SCHEMBL3299995 | 0.77 | KCNH2 (0.50) | KCNH2PGK1PGK2 | |
| SCHEMBL13819911 | 0.75 | CCR4 (0.33) | PDE2A | |
| SCHEMBL5259209 | 0.73 | GRM5 (0.41) | — | |
| SCHEMBL3470535 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |