SCHEMBL28020906

SCHEMBL28020906

O=Cc1cn[nH]c1CC=CF

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1845422 0.73
SCHEMBL16094240 0.73
SCHEMBL28058270 0.71 MEN1 (0.30)
SCHEMBL28001460 0.67
SCHEMBL6559445 0.67 LMNA (0.31) LMNA
SCHEMBL21670037 0.66
SCHEMBL314712 0.62
SCHEMBL3259059 0.62
SCHEMBL1844112 0.62
SCHEMBL4505993 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105555770-A Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1h-pyrazole-4-carbaldehyde BAYER CROPSCIENCE AG 2016-05-04 CN claimed
CN-102666492-B Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chloride BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-03-23 CN claimed
CN-105555770-A Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1h-pyrazole-4-carbaldehyde BAYER CROPSCIENCE AG 2016-05-04 CN disclosed
CN-102666492-B Process for preparing 5-fluoro-1-alkyl-3-fluoroalkyl-1H-pyrazole-4-carbonyl chloride BAYER INTELLECTUAL PROPERTY GMBH (DE) 2016-03-23 CN disclosed
CN-104918916-A Preparation method of 5-fluoro-1-methyl-3-difluoromethyl-1H-pyrazole-4-formaldehyde BAYER CROPSCIENCE AG 2015-09-16 CN disclosed
CN-104640845-A Method for the preparation of perfluoroalkyl containing pyrazoles carboxylates BAYER CROPSCIENCE AG 2015-05-20 CN disclosed