Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8646595 | 0.85 | AKR1B1 (0.49) | AKR1B1MAPTHSPA5ATMKDM4E | |
| SCHEMBL8634325 | 0.80 | AKR1B1 (0.62) | AKR1B1HSPA5CA12CA1CA2 | |
| SCHEMBL7008636 | 0.80 | CYP3A4 (0.58) | AKR1B1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL3107749 | 0.80 | CYP3A4 (0.58) | AKR1B1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL27701269 | 0.78 | AKR1B1 (0.60) | AKR1B1HSPA5CA12CA1CA2 | |
| SCHEMBL27674648 | 0.77 | L3MBTL1 (0.50) | ATML3MBTL1 | |
| SCHEMBL2722897 | 0.77 | CYP3A4 (0.64) | AKR1B1MAPTHSPA5KDM4ECYP3A4 | |
| SCHEMBL23706390 | 0.74 | PTGS1 (0.40) | MAPTKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL72309 | 0.72 | AKR1B1 (1.00) | AKR1B1MAPTHSPA5KDM4EMEN1 | |
| SCHEMBL30449014 | 0.72 | AKR1B1 (1.00) | AKR1B1MAPTHSPA5KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557901-A | Efficient production method of pyrimidofuranone | 湖北有宜新材料科技有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-104672146-A | New high-yield preparation method of azoxystrobin | SHANGHAI CAC CHEMICAL CO LTD | 2015-06-03 | — | — | CN | disclosed |