Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.72 |
| ▸ | PAX8 | Q06710 | 3/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | MITF | O75030 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | STAT6 | P42226 | 1/20 | 0.71 |
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20626317 | 1.00 | ADORA3 (0.72) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL20626318 | 1.00 | ADORA3 (0.72) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL14714035 | 1.00 | ADORA3 (0.72) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL14713281 | 1.00 | ADORA3 (0.72) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL17825992 | 1.00 | ADORA3 (0.72) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL19583113 | 1.00 | ADORA3 (0.72) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL17825957 | 0.90 | ADORA3 (0.69) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL19583002 | 0.90 | ADORA3 (0.69) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL19583100 | 0.90 | SLC29A1 (0.73) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 | |
| SCHEMBL17825928 | 0.90 | SLC29A1 (0.73) | ADORA3SLC29A1TP53PAX8SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102812033-B | N6-substituted adenosine derivatives and N6-substituted adenine derivatives and uses thereof | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2015-11-25 | — | — | CN | claimed |