SCHEMBL28021080

SCHEMBL28021080

Cc1cn(Br)c(=S)[nH]c1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.36
MAPK1 P28482 1/20 0.36
HPGD P15428 3/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ATAD2 Q6PL18 1/20 0.34
POLB P06746 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
GRIN2B Q13224 1/20 0.32
GRIN2C Q14957 1/20 0.32
GRIN3A Q8TCU5 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5176789 0.78 MAPK1 (0.46) TK1MAPK1HPGDATAD2POLB
SCHEMBL10105028 0.77 KMT2A (0.40) TK1MAPK1HPGDMEN1KMT2A
SCHEMBL28216800 0.75 MAPK1 (0.40) TK1MAPK1HPGDMEN1KMT2A
SCHEMBL23482940 0.75 MAPK1 (0.36) TK1MAPK1HPGDMEN1KMT2A
SCHEMBL29041555 0.73 ATAD2 (0.43) TK1MAPK1HPGDKMT2AATAD2
SCHEMBL24205178 0.72 MAPK1 (0.45) TK1MAPK1HPGDNPSR1ALDH1A1
SCHEMBL19888683 0.72 TDP1 (0.37) TK1MAPK1HPGDMEN1KMT2A
SCHEMBL8656137 0.72 SMN1; SMN2 (0.38) TK1MAPK1HPGDMEN1KMT2A
SCHEMBL6471981 0.71 MAPK1 (0.44) TK1MAPK1HPGDNPSR1ALDH1A1
SCHEMBL28799576 0.68 MAPK1 (0.41) TK1MAPK1HPGDTYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104781731-A Positive working photosensitive material AZ ELECTRONIC MATERIALS LUXEMBOURG SARL 2015-07-15 CN disclosed