Ethylene

Ethylene

SCHEMBL28021132

C=C.C=CC[N+](C)(C)Cc1ccccc1.[Cl-]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Ethylene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.44
ACHE known ✓ P22303 5/20 0.41
CHRM3 known ✓ P20309 1/20 0.35
ALDH1A1 P00352 3/20 0.52
KDM4E B2RXH2 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TP53 P04637 2/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTT P42858 2/20 0.46
DNM1 Q05193 2/20 0.44
CHRNA7 P36544 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.38
CXCR3 P49682 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11250018 0.98 ALDH1A1 (0.54) ALDH1A1KDM4ETDP1MEN1KMT2A
Hydrochloric Acid SCHEMBL21638 0.98 ALDH1A1 (0.54) ALDH1A1KDM4ETDP1MEN1KMT2A
Methane SCHEMBL28070367 0.96 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MEN1KMT2A
Hydrochloric Acid SCHEMBL11250021 0.96 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MEN1KMT2A
Water SCHEMBL8010252 0.96 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MEN1KMT2A
Hydrochloric Acid SCHEMBL28099309 0.96 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MEN1KMT2A
Hydrochloric Acid SCHEMBL11567888 0.96 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MEN1KMT2A
Bromide SCHEMBL3261137 0.96 ALDH1A1 (0.52) ALDH1A1KDM4ETDP1MEN1KMT2A
Hydrochloric Acid SCHEMBL11567898 0.96 ALDH1A1 (0.57) ALDH1A1KDM4ETDP1MEN1KMT2A
SCHEMBL130071 0.96 ALDH1A1 (0.50) ALDH1A1KDM4ETDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107325239-B A kind of high specific sulfanilamide (SN) trace quantum dot fluorescence sensor and preparation method thereof 长安大学 2019-07-05 CN claimed
CN-104744649-B A kind of preparation method of CdTe quantum fluorescence Cyhalothrin trace sensor 江苏大学 2018-06-26 CN claimed
CN-107325239-A A kind of high specific sulfanilamide (SN) trace quantum dot fluorescence sensor and preparation method thereof 长安大学 2017-11-07 CN claimed
CN-104744649-A Preparation method of CdTe quantum dot fluorescent cyfluthrin imprinted sensor UNIV JIANGSU 2015-07-01 CN claimed
CN-107325239-B A kind of high specific sulfanilamide (SN) trace quantum dot fluorescence sensor and preparation method thereof 长安大学 2019-07-05 CN disclosed
CN-107325239-B A kind of high specific sulfanilamide (SN) trace quantum dot fluorescence sensor and preparation method thereof 长安大学 2019-07-05 CN disclosed
CN-107325239-A A kind of high specific sulfanilamide (SN) trace quantum dot fluorescence sensor and preparation method thereof 长安大学 2017-11-07 CN disclosed
CN-107325239-A A kind of high specific sulfanilamide (SN) trace quantum dot fluorescence sensor and preparation method thereof 长安大学 2017-11-07 CN disclosed
CN-105062464-B A kind of preparation method of the quantum dot fluorescence trace sensor based on swelling techniques 江苏大学 2017-06-27 CN disclosed
CN-105062464-A Quantum dot fluorescence printing sensor preparation method based on swelling technology UNIV JIANGSU 2015-11-18 CN disclosed