SCHEMBL28021283

SCHEMBL28021283

COC(=O)C1C=CCC(C(=O)O)C1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABAT P80404 1/20 0.50
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA7 P36544 1/20 0.34
PPM1B O75688 1/20 0.33
PTPN1 P18031 1/20 0.33
PPP1CC P36873 1/20 0.33
CYP3A4 P08684 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11690581 0.89 CHRNB2 (0.40) ABATCHRNB2CHRNA4CHRNB4CHRNA3
SCHEMBL11690583 0.81 ABAT (0.46) ABATPPM1BPTPN1PPP1CCTSHR
SCHEMBL991477 0.81 ABAT (0.61) ABATCHRNB2CHRNA4CHRNA3CYP1A2
SCHEMBL6965861 0.80
SCHEMBL4859359 0.75 ABAT (0.40) ABATTSHRPOLB
SCHEMBL16922149 0.74 ABAT (0.53) ABAT
SCHEMBL14546542 0.71 CYP3A4 (0.32) CHRNB2CHRNA4CYP3A4CYP1A2CYP2D6
SCHEMBL17674194 0.71 MAPT (0.31)
SCHEMBL386334 0.71
SCHEMBL8122200 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102361861-B Method for producing epoxy compound SHOWA DENKO KABUSHIKI KAISHA (JP) 2015-09-02 CN disclosed