Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373545 | 0.81 | GRM3 (0.54) | — | |
| SCHEMBL28021364 | 0.78 | GABBR2 (0.42) | FFAR1ALDH1A1HPGDGABBR2GABBR1 | |
| SCHEMBL28021340 | 0.76 | TSHR (0.57) | TSHR | |
| SCHEMBL25362802 | 0.74 | FOLH1 (0.46) | — | |
| SCHEMBL27495226 | 0.73 | GABBR2 (0.46) | GABBR2GABBR1 | |
| SCHEMBL3825484 | 0.73 | GRM8 (0.49) | ALDH1A1RIPK1TSHRCYP2C19 | |
| SCHEMBL28092373 | 0.71 | FFAR1 (0.41) | FFAR1ALDH1A1HPGDRIPK1GABBR2 | |
| SCHEMBL27790851 | 0.71 | TAAR1 (0.50) | ALDH1A1RIPK1TRPA1 | |
| SCHEMBL1716157 | 0.71 | CYSLTR2 (0.50) | FFAR1ALDH1A1RIPK1TSHRTRPA1 | |
| SCHEMBL28021754 | 0.70 | CPA1 (0.43) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104873982-A | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2015-09-02 | — | — | CN | disclosed |
| CN-102014956-B | PSMA binding ligand-linker conjugates and methods of use thereof | PURDUE RESEARCH FOUNDATION | 2015-06-03 | — | — | CN | disclosed |