Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 4/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981802 | 0.81 | POLA1 (0.50) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL29337389 | 0.79 | CYP3A4 (0.49) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL18793793 | 0.79 | CYP3A4 (0.49) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL9628555 | 0.79 | SIGMAR1 (0.45) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL18793785 | 0.79 | CYP3A4 (0.49) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL13647384 | 0.78 | ADRA2A (0.49) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL7402146 | 0.78 | KDM4E (0.52) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL7446695 | 0.78 | POLA1 (0.45) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL30089469 | 0.77 | CYP3A4 (0.52) | POLA1SIGMAR1ADRB2HTR1AADRA2A | |
| SCHEMBL1091487 | 0.77 | CYP3A4 (0.52) | POLA1SIGMAR1ADRB2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085285-A | Method for preparing R-6-methoxy-1-aminoindane | WU LING | 2015-11-25 | — | — | CN | disclosed |
| CN-105001104-A | Method for preparing S-6-methoxy-1-aminoindane | WU LING | 2015-10-28 | — | — | CN | disclosed |