Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | CCR8 | P51685 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20837061 | 0.82 | L3MBTL1 (0.43) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL30038069 | 0.76 | L3MBTL1 (0.42) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL19667024 | 0.74 | TDP1 (0.42) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL3464293 | 0.74 | TDP1 (0.42) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL26126643 | 0.73 | LRRK2 (0.46) | L3MBTL1TDP1KMT2AKDM4ELMNA | |
| SCHEMBL12075250 | 0.72 | ALDH1A1 (0.63) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL19064531 | 0.72 | TDP1 (0.40) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL30492731 | 0.70 | TDP1 (0.43) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL28719367 | 0.70 | LRRK2 (0.42) | L3MBTL1TDP1HTTKMT2AALDH1A1 | |
| SCHEMBL3138188 | 0.68 | KDM4E (0.48) | L3MBTL1TDP1HTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672208-B | A kind of synthetic method of (3,5-bis trifluoromethyl pyrazolyl) pyridine derivate | 中国科学院大连化学物理研究所 | 2017-01-04 | — | — | CN | claimed |
| CN-104672208-A | Synthesis method of (3,5-bistrifluoromethylpyrazolyl)pyridine derivatives | DALIAN CHEMICAL PHYSICS INST | 2015-06-03 | — | — | CN | claimed |
| CN-104672208-B | A kind of synthetic method of (3,5-bis trifluoromethyl pyrazolyl) pyridine derivate | 中国科学院大连化学物理研究所 | 2017-01-04 | — | — | CN | disclosed |
| CN-104672208-B | A kind of synthetic method of (3,5-bis trifluoromethyl pyrazolyl) pyridine derivate | 中国科学院大连化学物理研究所 | 2017-01-04 | — | — | CN | disclosed |
| CN-104672208-B | A kind of synthetic method of (3,5-bis trifluoromethyl pyrazolyl) pyridine derivate | 中国科学院大连化学物理研究所 | 2017-01-04 | — | — | CN | disclosed |
| CN-104672208-A | Synthesis method of (3,5-bistrifluoromethylpyrazolyl)pyridine derivatives | DALIAN CHEMICAL PHYSICS INST | 2015-06-03 | — | — | CN | disclosed |
| CN-104672208-A | Synthesis method of (3,5-bistrifluoromethylpyrazolyl)pyridine derivatives | DALIAN CHEMICAL PHYSICS INST | 2015-06-03 | — | — | CN | disclosed |
| CN-104672208-A | Synthesis method of (3,5-bistrifluoromethylpyrazolyl)pyridine derivatives | DALIAN CHEMICAL PHYSICS INST | 2015-06-03 | — | — | CN | disclosed |