Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 3/20 | 0.64 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | OXTR | P30559 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR183 | P32249 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65277 | 0.85 | NNMT (0.68) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL28249567 | 0.82 | NNMT (0.64) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL28045755 | 0.82 | NNMT (0.64) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL18228074 | 0.81 | NNMT (0.72) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL29757598 | 0.79 | NNMT (0.70) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL29514668 | 0.79 | NNMT (0.70) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL105066 | 0.79 | NNMT (0.70) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL185291 | 0.79 | NNMT (0.70) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL10972399 | 0.79 | NNMT (0.60) | NNMTMKNK1MKNK2MAPK1KDM4E | |
| SCHEMBL2493127 | 0.78 | NNMT (0.68) | NNMTMKNK1MKNK2MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458956-B | The heterocycle sulfone that heteroaryl replaces | 格吕伦塔尔有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-104884435-A | Pyridone compound | KYOWA HAKKO KIRIN CO LTD | 2015-09-02 | — | — | CN | disclosed |