SCHEMBL28021937

SCHEMBL28021937

O=C(O)c1ccc(Oc2ccc(-c3ccccc3)c(Oc3ccc(C(=O)O)cc3)c2-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 3/20 0.47
TTR P02766 2/20 0.47
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
PARP15 Q460N3 1/20 0.41
PARP10 Q53GL7 1/20 0.41
FEN1 P39748 2/20 0.41
EGFR P00533 1/20 0.41
PKM P14618 1/20 0.41
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28021939 0.86 SRD5A2 (0.58) SRD5A2RXRARXRBRXRGPARP15
SCHEMBL28106291 0.85 AKR1C3 (0.55) TTRKDM4E
SCHEMBL454644 0.85 NCOA1 (0.43) TTRKDM4EHPGDPOLB
Phosphoric Acid SCHEMBL5679958 0.82 GPR84 (0.41) TTR
Phosphoric Acid SCHEMBL4371348 0.82 GPR84 (0.41) TTR
SCHEMBL23908714 0.82 RXRA (0.51) SRD5A2TTRRXRARXRBRXRG
SCHEMBL6823361 0.82 NCOA1 (0.39) TTRHPGD
SCHEMBL21177729 0.82 SRD5A2 (0.56) SRD5A2RXRARXRBRXRGPARP15
SCHEMBL11686004 0.79 SRD5A2 (0.50) SRD5A2TTRKDM4EHPGDPARP15
Pyrophosphoric Acid SCHEMBL1199532 0.79 GPR84 (0.38) TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414575-A Polyimide film having voids and method for manufacturing the same 旭化成株式会社 2017-02-15 CN disclosed
CN-104854165-A Resin precursor, resin composition containing the same, resin film and method for producing the same, and laminate and method for producing the same ASAHI KASEI E MATERIALS CORP 2015-08-19 CN disclosed