Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.31 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677008 | 0.98 | LMNA (0.37) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL10406453 | 0.78 | SLC6A2 (0.36) | LMNATRPA1HIF1AKDM4EHDAC8 | |
| SCHEMBL15067062 | 0.76 | LMNA (0.38) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL11442367 | 0.75 | ESR1 (0.34) | — | |
| SCHEMBL2444018 | 0.74 | LMNA (0.41) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL1776424 | 0.74 | TRPA1 (0.35) | LMNATRPA1TDP1 | |
| SCHEMBL16736879 | 0.73 | PTGS1 (0.43) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL1031444 | 0.73 | LMNA (0.35) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL10612043 | 0.73 | ESR1 (0.31) | LMNATRPA1PTGS1CACNA1CALDH1A1 | |
| SCHEMBL207770 | 0.73 | LMNA (0.33) | LMNAHTTTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854150-B | Activator compositions, their preparation, and their use in catalysts | 阿尔比马尔公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-103380154-B | Activator composition, its preparation and the purposes in catalysis thereof | 阿尔比马尔公司 | 2016-08-24 | — | — | CN | disclosed |
| CN-104854150-A | Activator compositions, their preparation, and their use in catalysts | ALBEMARLE CORP | 2015-08-19 | — | — | CN | disclosed |