Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31451585 | 0.86 | NPC1 (0.56) | TRPV1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1738423 | 0.86 | NPC1 (0.56) | TRPV1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1736457 | 0.78 | PAX8 (0.57) | TRPV1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14053640 | 0.78 | MAPT (0.40) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL8649480 | 0.78 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1ATM | |
| SCHEMBL444703 | 0.76 | ALDH1A1 (0.53) | TRPV1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1736168 | 0.75 | MEN1 (0.57) | TRPV1RAB9AKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1738384 | 0.75 | MAPT (0.52) | TRPV1RAB9AKMT2AMEN1ATM | |
| SCHEMBL27930436 | 0.75 | TRPV1 (0.51) | TRPV1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL8315587 | 0.75 | ALDH1A1 (0.43) | NPC1RAB9AKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104781234-A | Carboline and carbazole based imaging agents for detecting neurological dysfunction | LILLY CO ELI | 2015-07-15 | — | — | CN | disclosed |