SCHEMBL28022070

SCHEMBL28022070

N=C(N)NCCCC(N)(C(=O)O)C(=O)C(N)Cc1ccc(O)cc1

nearest known ligand 0.51

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.45
NPY4R P50391 13/20 0.44
NPY1R P25929 7/20 0.44
NPY2R P49146 5/20 0.43
NPY5R Q15761 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11199554 0.85 SLC7A5 (0.46) SLC7A5
SCHEMBL1711681 0.81 ALPI (0.44) SLC7A5
SCHEMBL6047676 0.81 ALPI (0.44) SLC7A5
SCHEMBL30631763 0.79 SLC7A5 (0.53) SLC7A5
Tyrosine SCHEMBL1551967 0.77 SLC7A5 (0.61) SLC7A5NPY4RNPY1RNPY2RNPY5R
SCHEMBL28722500 0.76 SLC7A5 (0.37) SLC7A5NPY4RNPY1RNPY2RNPY5R
Tyrosine SCHEMBL29245680 0.75 SLC7A5 (0.58) SLC7A5NPY4RNPY1RNPY2RNPY5R
SCHEMBL27999442 0.75 NPY4R (0.39) SLC7A5NPY4RNPY1RNPY2RNPY5R
Tyrosine SCHEMBL28525429 0.75 SLC7A5 (0.55) SLC7A5NPY4RNPY1RNPY2RNPY5R
SCHEMBL9301763 0.74 CTSL (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104884152-B Method for improving rejection of reverse osmosis membrane, rejection improving agent, and reverse osmosis membrane 栗田工业株式会社 2017-10-13 CN disclosed
CN-104884152-A Method for improving rejection of reverse osmosis membrane, rejection improving agent, and reverse osmosis membrane KURITA WATER IND LTD 2015-09-02 CN disclosed