Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12319880 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL28062463 | 0.84 | PPARG (0.42) | ALDH1A1TYRPPARGPPARACA12 | |
| SCHEMBL11200803 | 0.79 | ALDH1A1 (0.56) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL1560391 | 0.79 | CYP4F2 (0.53) | ALDH1A1TYRCA12CA1CA4 | |
| SCHEMBL27637243 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TYRCA12CA1CA4 | |
| SCHEMBL1992145 | 0.79 | CYP4F2 (0.53) | ALDH1A1TYRCA12CA1CA4 | |
| SCHEMBL13034103 | 0.79 | ALOX5 (0.53) | ALDH1A1CA12CA1CA4CA6 | |
| SCHEMBL27608519 | 0.79 | TYR (0.61) | ALDH1A1TYRCA12CA1CA4 | |
| SCHEMBL28201295 | 0.78 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2NPC1TP53MAPK1 | |
| SCHEMBL17420467 | 0.78 | ALDH1A1 (0.44) | ALDH1A1TYRSMN1; SMN2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104812756-A | Multiple kinase pathway inhibitors | MANNKIND CORP | 2015-07-29 | — | — | CN | disclosed |