Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74363 | 0.97 | AHR (0.54) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL74364 | 0.97 | AHR (0.54) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL29190657 | 0.80 | HDAC3 (0.50) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL699666 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL1795502 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL9679429 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL20582895 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL260347 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL9679426 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL10458457 | 0.80 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768932-B | The heteroaryl inhibitors of PDE4 | 泰特拉探索合伙有限责任公司 | 2018-08-07 | — | — | CN | disclosed |
| CN-104768932-A | Heteroaryl inhibitors of PDE4 | TETRA DISCOVERY PARTNERS LLC | 2015-07-08 | — | — | CN | disclosed |