Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL74364 | 1.00 | AHR (0.54) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL28022158 | 0.97 | AHR (0.52) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL29190657 | 0.82 | HDAC3 (0.50) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL699666 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL9679429 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL1795502 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL20582895 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL260347 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL9679426 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA | |
| SCHEMBL10458457 | 0.82 | AHR (0.74) | AHRCYP1A2HSD17B10FBP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030232994-A1 | Bicyclic thiophene derivatives and combinatorial libraries thereof | LION BIOSCIENCE AG (DE) | 2003-12-18 | — | — | US | claimed |
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | claimed |
| EP-0983507-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | Trega Biosciences, Inc. (US) | 2000-03-08 | — | — | EP | claimed |
| WO-1998034111-A1 | TRICYCLIC TETRAHYDROQUINOLINE DERIVATIVES AND TRICYCLIC TETRAHYDROQUINOLINE COMBINATORIAL LIBRARIES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
| US-5786448-A | FOR SCREENING, SYNTHESIZING PEPTIDE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-07-28 | — | — | US | claimed |
| WO-1998019693-A1 | COMBINATORIAL LIBRARIES OF CYCLIC UREA AND CYCLIC THIOUREA DERIVATIVES AND COMPOUNDS THEREIN | TREGA BIOSCIENCES, INC. (US) | 1998-05-14 | — | — | WO | claimed |
| US-5026838-A | Starting materials for polynucleotides | NIPPON ZEON CO., LTD. (JP) | 1991-06-25 | — | — | US | claimed |
| US-4981873-A | ANTICOAGULANTS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-01-01 | — | — | US | claimed |
| US-4906768-A | Process for production of oxime derivatives | NIPPON ZEON CO., LTD. (JP) | 1990-03-06 | — | — | US | claimed |
| EP-0065407-B1 | PHARMACEUTICAL SPIRO-SUCCINIMIDE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-13 | — | — | EP | claimed |
| EP-0065407-A2 | Pharmaceutical spiro-succinimide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | claimed |
| US-3956374-A | Aryl-oxo-heptenoic acids | MERCK & CO., INC. (US) | 1976-05-11 | — | — | US | claimed |
| CN-114656380-B | Method for simply synthesizing allyl thiomethyl ether | 南阳师范学院 | 2023-06-02 | — | — | CN | disclosed |
| CN-115558686-A | Method for synthesizing cinnamamide derivatives on line based on continuous flow bioreactor | 浙江工业大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-114656380-A | Method for simply synthesizing allyl methyl sulfide | 南阳师范学院 | 2022-06-24 | — | — | CN | disclosed |
| EP-1515969-B2 | SPIROINDOLINEPIPERIDINE DERIVATIVES | SYNGENTA LTD (GB) | 2017-10-11 | — | — | EP | disclosed |
| EP-0065407-A2 | Pharmaceutical spiro-succinimide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-24 | — | — | EP | disclosed |
| US-4249027-A | Process for the preparation of 5-substituted resorcinols and related intermediates | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |
| US-4045434-A | Esters of nitro(tetrahydro-2H-1,3-thiazin-2-ylidene)acetic acids | SHELL OIL COMPANY (US) | 1977-08-30 | — | — | US | disclosed |
| US-4020098-A | Process for the preparation of 5-substituted resorcinols and related intermediates | CIBA-GEIGY CORPORATION (US) | 1977-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232994-A1 | Bicyclic thiophene derivatives and combinatorial libraries thereof | CXCR2, BICRA, CXCR1 | AHR 1614/4885CYP1A2 199/4885HSD17B10 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.