Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 14/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 7/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 2/20 | 0.33 |
| ▸ | CDK8 | P49336 | 2/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31165744 | 0.82 | KDM4C (0.46) | KDM4CHTTKDM6BKDM4DTDP1 | |
| SCHEMBL28022167 | 0.82 | HTT (0.38) | HTTTDP1KDM4EALDH1A1MAPT | |
| SCHEMBL22589227 | 0.73 | HPGD (0.34) | HTTKDM4EALDH1A1MAPTRECQL | |
| SCHEMBL22589228 | 0.73 | HPGD (0.34) | HTTKDM4EALDH1A1MAPTRECQL | |
| SCHEMBL9000661 | 0.72 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL29956489 | 0.71 | KDM4C (0.50) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL10526340 | 0.71 | KDM4C (0.50) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL27185866 | 0.71 | CYP11B1 (0.50) | KDM4CKDM6BKDM4DTDP1KDM4E | |
| SCHEMBL29856256 | 0.68 | CCNC (0.51) | HTTTDP1KDM4EMEN1ALDH1A1 | |
| SCHEMBL4049897 | 0.68 | PTPN1 (0.42) | KDM4CKDM6BKDM4DTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736543-A | 7-azaindol-2,7-naphthyridine derivative for the treatment of tumors | MERCK PATENT GMBH | 2015-06-24 | — | — | CN | disclosed |