Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 15/20 | 0.50 |
| ▸ | KDM6B | O15054 | 7/20 | 0.50 |
| ▸ | KDM4D | Q6B0I6 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KDM4A | O75164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526340 | 1.00 | KDM4C (0.50) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL547927 | 0.84 | KDM4C (0.55) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL16217237 | 0.82 | TDP1 (0.43) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL9000661 | 0.78 | KDM4C (0.44) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL7899172 | 0.78 | ERN1 (0.38) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL14097049 | 0.78 | NUDT1 (0.44) | KDM4CKDM6BTDP1ALDH1A1KDM4E | |
| SCHEMBL5834304 | 0.78 | ALDH1A1 (0.56) | TDP1ALDH1A1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL2560775 | 0.78 | EIF4E (0.42) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL27185866 | 0.77 | CYP11B1 (0.50) | KDM4CKDM6BKDM4DTDP1ALDH1A1 | |
| SCHEMBL29416303 | 0.76 | KDM4C (0.65) | KDM4CKDM6BKDM4DTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |