Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 3/20 | 0.35 |
| ▸ | CDK8 | P49336 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitrous Acid SCHEMBL28022168 | 0.82 | KDM4C (0.39) | HTTSIRT3TDP1CCNCCDK8 | |
| SCHEMBL31165744 | 0.72 | KDM4C (0.46) | HTTTDP1KDM4EALDH1A1MAPT | |
| SCHEMBL29856256 | 0.67 | CCNC (0.51) | HTTTDP1CCNCCDK8KDM4E | |
| SCHEMBL9000657 | 0.67 | KDM4E (0.50) | HTTSIRT3TDP1CCNCCDK8 | |
| SCHEMBL28904581 | 0.66 | KMT2A (0.46) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL29105405 | 0.66 | ALDH1A1 (0.67) | SIRT3TDP1KDM4EALDH1A1GLA | |
| SCHEMBL28552197 | 0.66 | RAB9A (0.48) | TDP1KDM4EALDH1A1GLAGAA | |
| SCHEMBL28930016 | 0.66 | TSHR (0.45) | CCNCCDK8KDM4EALDH1A1NPC1 | |
| SCHEMBL5834304 | 0.65 | ALDH1A1 (0.56) | HTTSIRT3TDP1KDM4EALDH1A1 | |
| SCHEMBL4899871 | 0.65 | ALDH1A1 (0.40) | HTTALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736543-A | 7-azaindol-2,7-naphthyridine derivative for the treatment of tumors | MERCK PATENT GMBH | 2015-06-24 | — | — | CN | disclosed |