Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.58 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5389333 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL30472877 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL5350154 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL5352695 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL4892697 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL14777978 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL538461 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL15538720 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL2772680 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL9125508 | 0.95 | SLC22A1 (0.68) | SLC22A1ALDH1A1TSHRHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110507555-A | A kind of anhydrous amino acid ginger tea shampoo and its processing method | GUIZHOU MUMU XIYAN BIO TECH CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-108904313-A | A kind of shower cream and preparation method thereof with skin-moistening effect | 广州欧凡化妆品有限公司 | 2018-11-30 | — | — | CN | claimed |
| CN-105101798-A | Cationic pyrithione dispersion | ARCH PERSONAL CARE PRODUCTS LP | 2015-11-25 | — | — | CN | claimed |
| CN-110507555-A | A kind of anhydrous amino acid ginger tea shampoo and its processing method | GUIZHOU MUMU XIYAN BIO TECH CO LTD | 2019-11-29 | — | — | CN | disclosed |
| CN-108904313-A | A kind of shower cream and preparation method thereof with skin-moistening effect | 广州欧凡化妆品有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-108904313-A | A kind of shower cream and preparation method thereof with skin-moistening effect | 广州欧凡化妆品有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-105101798-A | Cationic pyrithione dispersion | ARCH PERSONAL CARE PRODUCTS LP | 2015-11-25 | — | — | CN | disclosed |