Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 13/20 | 0.57 |
| ▸ | NOS3 | P29474 | 9/20 | 0.57 |
| ▸ | NOS1 | P29475 | 9/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1711216 | 1.00 | NOS2 (0.57) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL1711214 | 1.00 | NOS2 (0.57) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2194273 | 0.88 | NOS2 (0.74) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2194274 | 0.88 | NOS2 (0.74) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2194276 | 0.88 | NOS2 (0.74) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL1710952 | 0.85 | PTPN2 (0.55) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL1710949 | 0.85 | PTPN2 (0.55) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL28820831 | 0.84 | CYP3A4 (0.58) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2190277 | 0.84 | CYP3A4 (0.58) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2190274 | 0.84 | CYP3A4 (0.58) | NOS2NOS3NOS1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102216260-B | Amino acid derivative | NIPPON ZOKI PHARMACEUTICAL CO | 2015-07-15 | — | — | CN | disclosed |