Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NOS2 | P35228 | 7/20 | 0.53 |
| ▸ | NOS3 | P29474 | 6/20 | 0.52 |
| ▸ | NOS1 | P29475 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190274 | 1.00 | CYP3A4 (0.58) | CYP3A4CYP2C19GAANOS2NOS3 | |
| SCHEMBL28820831 | 1.00 | CYP3A4 (0.58) | CYP3A4CYP2C19GAANOS2NOS3 | |
| SCHEMBL1711285 | 0.88 | PTPN2 (0.50) | CYP3A4CYP2C19GAAPTPN2PTPN1 | |
| SCHEMBL1711573 | 0.88 | PTPN2 (0.50) | CYP3A4CYP2C19GAAPTPN2PTPN1 | |
| SCHEMBL1711214 | 0.84 | NOS2 (0.57) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL28022277 | 0.84 | NOS2 (0.57) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL1711216 | 0.84 | NOS2 (0.57) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2194273 | 0.82 | NOS2 (0.74) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2194276 | 0.82 | NOS2 (0.74) | NOS2NOS3NOS1PTPN2PTPN1 | |
| SCHEMBL2194274 | 0.82 | NOS2 (0.74) | NOS2NOS3NOS1PTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150510-B2 | Amino acid derivative | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20110172442-A1 | AMINO ACID DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172442-A1 | AMINO ACID DERIVATIVE | OPRL1, OPRK1, SLC1A1 | CYP3A4 4061/4885CYP2C19 3832/4885GAA 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.