Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14763948 | 0.92 | THRB (1.00) | THRBLMNA | |
| SCHEMBL18928 | 0.92 | THRB (1.00) | THRBLMNA | |
| Hydrochloric Acid SCHEMBL31648719 | 0.88 | THRB (0.92) | THRBLMNA | |
| Ammonia Solution, Strong SCHEMBL28342116 | 0.88 | THRB (0.92) | THRBLMNA | |
| Alcohol SCHEMBL3582748 | 0.81 | THRB (0.79) | THRBLMNA | |
| Methylene Chloride SCHEMBL4405315 | 0.81 | THRB (0.79) | THRBLMNA | |
| SCHEMBL9873559 | 0.79 | THRB (0.73) | THRBLMNA | |
| Calcium Chloride SCHEMBL27621196 | 0.79 | THRB (0.73) | THRBLMNA | |
| SCHEMBL4666770 | 0.79 | THRB (0.73) | THRBLMNA | |
| SCHEMBL868849 | 0.77 | THRB (0.71) | THRBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104703980-A | Orexin receptor antagonists which are [ortho bi (hetero )aryl]-[2-(meta bi (hetero )aryl)-pyrrolidin-1-yl]-methanone derivatives | ACTELION PHARMACEUTICALS LTD | 2015-06-10 | — | — | CN | disclosed |