SCHEMBL9873559

SCHEMBL9873559

CCOC(OCC)OCC.COC(OC)OC

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.73
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3179171 0.90
SCHEMBL14706244 0.90
SCHEMBL18928 0.86 THRB (1.00) THRBLMNA
SCHEMBL14763948 0.86 THRB (1.00) THRBLMNA
SCHEMBL28143 0.84 THRB (0.59) THRBLMNA
Ammonia Solution, Strong SCHEMBL28342116 0.82 THRB (0.92) THRBLMNA
Hydrochloric Acid SCHEMBL31648719 0.82 THRB (0.92) THRBLMNA
SCHEMBL27743970 0.79 LMNA (0.58) THRBLMNA
SCHEMBL5847043 0.79
SCHEMBL9114593 0.79 THRB (0.53) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5051444-A Pyrrolidine derivatives as anti-amnesia agents SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1991-09-24 US disclosed
US-4880827-A Pyrrolidine derivatives having inhibitory action for proline specific endopepidase SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) 1989-11-14 US disclosed
EP-0238319-A1 Pyrrolidine derivatives SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1987-09-23 EP disclosed