Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 2/20 | 0.35 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28184370 | 0.88 | ACACB (0.35) | GRNSORT1MEN1KMT2ARECQL | |
| SCHEMBL28022836 | 0.86 | ACACB (0.38) | MEN1KMT2ARECQLCA2MAPK1 | |
| SCHEMBL28023398 | 0.86 | ACACB (0.38) | MEN1KMT2ARECQLCA2MAPK1 | |
| SCHEMBL28022806 | 0.81 | MEN1 (0.33) | MEN1KMT2ACYP2C19RECQL | |
| SCHEMBL28022708 | 0.81 | GAA (0.38) | GRNSORT1MEN1KMT2AGAA | |
| SCHEMBL28023389 | 0.80 | CHRM1 (0.44) | MEN1KMT2ACYP2C19RECQLCA2 | |
| SCHEMBL1396424 | 0.80 | CHRM1 (0.44) | MEN1KMT2ACYP2C19RECQLCA2 | |
| SCHEMBL14296151 | 0.77 | FAAH (0.37) | MEN1KMT2ACYP2C19RECQL | |
| SCHEMBL28022744 | 0.77 | CA2 (0.45) | CA2MAPK1CHRM1AKR1A1CHRM3 | |
| SCHEMBL28022897 | 0.77 | FOLH1 (0.38) | MEN1KMT2ACYP2C19RECQLFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755510-A | Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same | INDIAN OIL CORP LTD | 2015-07-01 | — | — | CN | claimed |
| CN-104755510-A | Ziegler-Natta catalyst systems comprising a 1,2-phenylenedioate as internal donor and process for preparing the same | INDIAN OIL CORP LTD | 2015-07-01 | — | — | CN | disclosed |