Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrazine SCHEMBL28030851 | 0.65 | NFKB1 (0.32) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL18382542 | 0.64 | — | — | |
| SCHEMBL27491016 | 0.64 | NFKB1 (0.33) | MAPTKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4773453 | 0.59 | KDM4E (0.36) | MAPTKDM4ECYP1A2MEN1ALDH1A1 | |
| SCHEMBL5210633 | 0.57 | TSHR (0.39) | MAPTKDM4ELMNAMEN1ALDH1A1 | |
| SCHEMBL27367444 | 0.57 | NFKB1 (0.38) | MAPTKDM4ECYP1A2MEN1ALDH1A1 | |
| SCHEMBL21688998 | 0.57 | MEN1 (0.35) | MAPTKDM4ELMNACYP1A2CYP3A4 | |
| SCHEMBL1087748 | 0.56 | MEN1 (0.37) | MAPTKDM4ECYP1A2MEN1ALDH1A1 | |
| SCHEMBL7067843 | 0.56 | MEN1 (0.37) | MAPTKDM4ECYP1A2MEN1ALDH1A1 | |
| SCHEMBL9879740 | 0.56 | RAB9A (0.42) | MAPTKDM4ELMNACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104804008-B | A kind of method of suitability for industrialized production methylsulfonic acid Telatinib | Yiteng Pharmaceutical (Taizhou) Co. Ltd. (CN) | 2016-03-23 | — | — | CN | claimed |
| CN-104804008-A | Industrial production method of telatinib mesylate | EDDINGPHARM TAIZHOU CO LTD | 2015-07-29 | — | — | CN | claimed |
| CN-104804008-B | A kind of method of suitability for industrialized production methylsulfonic acid Telatinib | Yiteng Pharmaceutical (Taizhou) Co. Ltd. (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-104804008-B | A kind of method of suitability for industrialized production methylsulfonic acid Telatinib | Yiteng Pharmaceutical (Taizhou) Co. Ltd. (CN) | 2016-03-23 | — | — | CN | disclosed |
| CN-104804008-A | Industrial production method of telatinib mesylate | EDDINGPHARM TAIZHOU CO LTD | 2015-07-29 | — | — | CN | disclosed |